Assistant Professor (RTT) in Genetics
Dept. of Biology · since Sept 2024
University of Pisa — Official ProfileManuel
Gentiluomo
I am a geneticist and genetic epidemiologist working on the molecular basis of pancreatic cancer and its precursor lesions. My research combines large-scale genome-wide association studies (GWAS), long-read sequencing, and international collaborative networks to identify germline risk factors and improve precision prevention.
I coordinate the PANDoRA consortium database and actively participate in the COST Action TRANSPAN across European partners. Previously a post-doctoral fellow at Fondazione Umberto Veronesi.
Active Projects
World's largest GWAS on panNEN
International coordination to identify germline susceptibility loci for pancreatic neuroendocrine neoplasms. Meta-analysis across European and North American cohorts (Mayo Clinic, Dana-Farber, NIH, PANDoRA).
Structural Variants in PDAC — Human Technopole
Mapping germline structural variants in pancreatic ductal adenocarcinoma using Oxford Nanopore long-read sequencing. Funded by the Human Technopole National Facility for Genomics (ONT WGS, 32 samples, 20–30X · ~€50k value).
GWAS Pipeline — Open-source guide & code
A methodological review and reproducible codebase documenting the full GWAS analysis pipeline — from quality control to post-GWAS interpretation. Code available on GitHub.
Latest from Bluesky
Follow →Open to collaborations
Looking for motivated BSc and MSc students in Molecular Genetics or Bioinformatics.